reasoning benchmark
BioMysteryBench Leaderboard
BioMysteryBench evaluates a model's ability to reason through challenging molecular biology problems, reporting performance on a hard subset and on the subset of problems solved by human experts.
Updated Aug 17, 2026
Models3
Model coverage3
MetricScore
EvidenceB
BioMysteryBench Ranking
Higher score ranks better on this benchmark.
Sort by
Rank | Model | Score | Percentile | Participants | Evidence | Evaluated |
|---|
| Rank01 | ModelAN | Score90.1% | Percentile100.0% | Participants3 | EvidenceC | Evaluated |
| Rank02 | ModelAN | Score46.1% | Percentile50.0% | Participants3 | EvidenceC | Evaluated |
| Rank03 | ModelGO | Score43.5% | Percentile0.0% | Participants3 | EvidenceC | Evaluated |
BioMysteryBench Highlights
The leading models and scores on this benchmark.
BioMysteryBench Score Distribution
A closer view of the leading scores on this benchmark.
The Top AI Models for BioMysteryBench
The first five results on this benchmark, with official price and output speed added where the model identity can be matched.
Ranking basisThis biomysterybench AI model leaderboard uses descending score in the benchmark's original unit. The leaderboard ranking keeps matched price and speed data separate from benchmark evidence.
- 01ANClaude Opus 5Anthropic
- Score
- 90.1%
- Price
- $5.0 input / $25 output per 1M tokens
- Speed
- Up to 3.3 tok/s via Anthropic
Strengths
- Ranks #1 of 3 compared models
- 100th percentile on this benchmark
- C evidence result
Considerations
- This result measures BioMysteryBench, not total model capability
- 02ANClaude Fable 5Anthropic
- Score
- 46.1%
- Price
- $10 input / $50 output per 1M tokens
- Speed
- Up to 9.1 tok/s via Anthropic
Strengths
- Ranks #2 of 3 compared models
- 50th percentile on this benchmark
- C evidence result
Considerations
- This result measures BioMysteryBench, not total model capability
- 03GOGemini 3.7 FlashGoogle
- Score
- 43.5%
- Price
- $0.75 input / $3.8 output per 1M tokens
- Speed
- Up to 13 tok/s via Google
Strengths
- Ranks #3 of 3 compared models
- 0th percentile on this benchmark
- C evidence result
Considerations
- This result measures BioMysteryBench, not total model capability
Selection summary
Best AI Models for BioMysteryBench
Claude Opus 5 currently leads BioMysteryBench with 90.1%. It is the top model on this specific benchmark, while the best LLM for the broader task should also be checked against other benchmarks, price and runtime.
Use this leaderboard with the supporting benchmark results and coverage details above. A leaderboard position summarizes the selected ranking signal; it does not replace workload-specific testing.
What is BioMysteryBench?
What BioMysteryBench measures and how its scores work.
BioMysteryBench evaluates a model's ability to reason through challenging molecular biology problems, reporting performance on a hard subset and on the subset of problems solved by human experts.
Scores are shown in ratio. This benchmark is not independently verified and has an evidence level of B.
- Family
- BioMysteryBench
- Modality
- text
- Primary category
- reasoning
- Score direction
- higher
- LLMBoard eligible
- Yes
- Evaluation key
- biomysterybench|llm-stats-current
Benchmark scores retain their original unit. Overall score eligibility is shown separately.
FAQ
Common questions about BioMysteryBench.
Which model scores highest on BioMysteryBench?
Claude Opus 5 is currently ranked first with 90.1%.
What does BioMysteryBench measure?
BioMysteryBench evaluates a model's ability to reason through challenging molecular biology problems, reporting performance on a hard subset and on the subset of problems solved by human experts.
Is a higher score better?
Yes. Higher values rank better for this benchmark.
How many models are compared?
3 model results are currently shown.
Does this benchmark affect the overall score?
Yes. This benchmark can contribute to the current LLMBoard capability score.