reasoning benchmark
BioMysteryBench evaluates a model's ability to reason through challenging molecular biology problems, reporting performance on a hard subset and on the subset of problems solved by human experts.
Updated Aug 11, 2026
Higher score ranks better on this benchmark.
| 01 | AN | 90.1% | 100.0% | 2 | C | |
| 02 | AN | 46.1% | 0.0% | 2 | C |
A closer view of the leading scores on this benchmark.
The leading models and scores on this benchmark.
What BioMysteryBench measures and how its scores work.
BioMysteryBench evaluates a model's ability to reason through challenging molecular biology problems, reporting performance on a hard subset and on the subset of problems solved by human experts.
Scores are shown in ratio. This benchmark is not independently verified and has an evidence level of B.
Benchmark scores retain their original unit. Overall score eligibility is shown separately.
Common questions about BioMysteryBench.
Claude Opus 5 is currently ranked first with 90.1%.
BioMysteryBench evaluates a model's ability to reason through challenging molecular biology problems, reporting performance on a hard subset and on the subset of problems solved by human experts.
Yes. Higher values rank better for this benchmark.
2 model results are currently shown.
No. This benchmark is shown for reference but does not contribute to the overall score.